Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4716342 | 0.83 | BDKRB1 (0.77) | BDKRB1CYP1A2CYP3A4USP2MEN1 | |
| SCHEMBL4717762 | 0.81 | BDKRB1 (0.74) | BDKRB1CYP1A2CYP3A4USP2MEN1 | |
| SCHEMBL1712902 | 0.80 | BDKRB1 (1.00) | BDKRB1CYP1A2CYP3A4USP2MEN1 | |
| SCHEMBL4712523 | 0.80 | BDKRB1 (0.72) | BDKRB1CYP1A2CYP3A4USP2MEN1 | |
| SCHEMBL4714147 | 0.77 | BDKRB1 (0.69) | BDKRB1CYP1A2CYP3A4USP2MEN1 | |
| SCHEMBL4760693 | 0.76 | BDKRB1 (0.66) | BDKRB1USP2MAPK1ALDH1A1TSHR | |
| SCHEMBL4716862 | 0.74 | BDKRB1 (0.64) | BDKRB1USP2MEN1KMT2AMAPK1 | |
| SCHEMBL4714259 | 0.73 | BDKRB1 (0.60) | BDKRB1MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL4759441 | 0.73 | BDKRB1 (0.84) | BDKRB1CYP1A2CYP3A4USP2MEN1 | |
| SCHEMBL4716396 | 0.73 | BDKRB1 (0.61) | BDKRB1MEN1KMT2APARP1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008153967-A1 | BK1 ANTAGONIST CONJUGATES | CONTEC THERAPEUTICS, INC. (US) | 2008-12-18 | — | — | WO | disclosed |