Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.56 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.56 |
| ▸ | BDKRB1 | P46663 | 11/20 | 0.56 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.56 |
| ▸ | EEF2K | O00418 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652039 | 1.00 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1BDKRB1BDKRB2 | |
| SCHEMBL644240 | 0.90 | EEF2K (0.66) | SLC1A3SLC1A2SLC1A1BDKRB1BDKRB2 | |
| SCHEMBL3310158 | 0.90 | EEF2K (0.66) | SLC1A3SLC1A2SLC1A1BDKRB1BDKRB2 | |
| SCHEMBL13780961 | 0.85 | CYP1A2 (0.55) | SLC1A3SLC1A2SLC1A1BDKRB1BDKRB2 | |
| SCHEMBL2933326 | 0.85 | CYP1A2 (0.55) | SLC1A3SLC1A2SLC1A1BDKRB1BDKRB2 | |
| SCHEMBL26606040 | 0.83 | SLC1A3 (0.61) | SLC1A3SLC1A2SLC1A1ALDH1A1F2 | |
| SCHEMBL26606049 | 0.83 | SLC1A3 (0.61) | SLC1A3SLC1A2SLC1A1ALDH1A1F2 | |
| SCHEMBL12317324 | 0.82 | GAA (0.56) | SLC1A3SLC1A2SLC1A1BDKRB1BDKRB2 | |
| SCHEMBL6953103 | 0.81 | EEF2K (0.56) | SLC1A3SLC1A2SLC1A1BDKRB1BDKRB2 | |
| SCHEMBL3441384 | 0.81 | BDKRB1 (0.51) | SLC1A3SLC1A2SLC1A1BDKRB1BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008153967-A1 | BK1 ANTAGONIST CONJUGATES | CONTEC THERAPEUTICS, INC. (US) | 2008-12-18 | — | — | WO | disclosed |