Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398521 | 0.93 | HCRTR1 (0.86) | HCRTR1HCRTR2 | |
| SCHEMBL1398588 | 0.93 | HCRTR1 (0.86) | HCRTR1HCRTR2 | |
| SCHEMBL1398721 | 0.93 | HCRTR1 (0.86) | HCRTR1HCRTR2 | |
| SCHEMBL1398745 | 0.93 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL4739234 | 0.88 | HCRTR1 (0.68) | HCRTR1HCRTR2 | |
| SCHEMBL4739920 | 0.88 | HCRTR1 (0.69) | HCRTR1HCRTR2 | |
| SCHEMBL4738336 | 0.88 | HCRTR1 (0.68) | HCRTR1HCRTR2 | |
| SCHEMBL4785147 | 0.87 | HCRTR1 (0.68) | HCRTR1HCRTR2 | |
| SCHEMBL3640876 | 0.86 | HCRTR1 (0.66) | HCRTR1HCRTR2 | |
| SCHEMBL1572210 | 0.86 | HCRTR1 (0.88) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994336-B2 | Azetidine compounds as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-08-09 | — | — | US | claimed |
| EP-2069332-B1 | AZETIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-03-02 | — | — | EP | claimed |
| US-7994336-B2 | Azetidine compounds as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-08-09 | — | — | US | disclosed |
| EP-2069332-B1 | AZETIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-03-02 | — | — | EP | disclosed |
| EP-1973960-B1 | POLYESTER OLIGOMERS, METHODS OF MAKING, AND THERMOSETTING COMPOSITIONS FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP (NL) | 2011-03-02 | — | — | EP | disclosed |
| EP-1973960-A2 | POLYESTER OLIGOMERS, METHODS OF MAKING, AND THERMOSETTING COMPOSITIONS FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007081539-A2 | POLYESTER OLIGOMERS, METHODS OF MAKING, AND THERMOSETTING COMPOSITIONS FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2007-07-19 | — | — | WO | disclosed |
| US-20070155946-A1 | Polyester oligomers, methods of making, and thermosetting compositions formed therefrom | CITIBANK, N.A., AS COLLATERAL AGENT | 2007-07-05 | — | — | US | disclosed |