Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13059797 | 1.00 | MAPT (0.50) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL13059798 | 1.00 | MAPT (0.50) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL4072294 | 0.88 | MAPT (0.50) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL3538785 | 0.88 | MAPT (0.50) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL3535329 | 0.88 | MAPT (0.50) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL3540797 | 0.88 | MAPT (0.50) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL3536137 | 0.88 | MAPT (0.50) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL2795742 | 0.87 | MAPT (0.52) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL2795738 | 0.87 | MAPT (0.52) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL22034017 | 0.87 | MAPT (0.52) | MAPTPDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470709-B2 | Benzimidazole quinolinones and uses thereof | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2008-12-30 | — | — | US | disclosed |