SCHEMBL13985607

SCHEMBL13985607

C1=C(c2c3ccccc3c(-c3cccc4c3ccc3cc5ccccc5cc34)c3ccccc23)CCC(n2c(-c3ccccc3)nc3ccccc32)=C1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.35
ESR2 Q92731 4/20 0.35
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
GSR P00390 1/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
RAB9A P51151 1/20 0.31
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
MAPK10 P53779 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22754701 0.85 ESR1 (0.39) ESR1ESR2KDM4EALDH1A1HPGD
SCHEMBL13249113 0.85 ESR1 (0.41) ESR1ESR2KDM4EALDH1A1HPGD
SCHEMBL12831669 0.83 GSR (0.32) ESR1ESR2GSRRAB9AMAPK10
SCHEMBL13249114 0.82 ESR1 (0.49) ESR1ESR2KDM4EALDH1A1HPGD
SCHEMBL23768277 0.81 ESR1 (0.39) ESR1ESR2KDM4EALDH1A1HPGD
SCHEMBL9612379 0.81 ESR1 (0.44) ESR1ESR2ALDH1A1MEN1GAA
SCHEMBL21181334 0.81 ESR1 (0.39) ESR1ESR2KDM4EALDH1A1HPGD
SCHEMBL13249120 0.79 ESR1 (0.46) ESR1ESR2KDM4EALDH1A1HPGD
SCHEMBL8780660 0.77 ESR1 (0.41) ESR1ESR2KDM4EALDH1A1HPGD
SCHEMBL13249102 0.77 GSR (0.42) ESR1ESR2KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008145239-A2 BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2008-12-04 WO disclosed