SCHEMBL13986632

SCHEMBL13986632

CCCCCN1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(CCCN1C(=O)c2ccc3c4ccc6c7c(ccc(c8ccc(c2c38)C1=O)c74)C(=O)N(CCCCC)C6=O)C5=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.65
▸ HIF1A Q16665 1/20 0.65
▸ TERT O14746 7/20 0.59
▸ MEN1 O00255 2/20 0.57
▸ RGS12 O14924 2/20 0.57
▸ HTT P42858 2/20 0.57
▸ KMT2A Q03164 2/20 0.57
▸ ALDH1A1 P00352 2/20 0.57
▸ KDM4E B2RXH2 1/20 0.57
▸ NPC1 O15118 1/20 0.57
▸ LMNA P02545 1/20 0.57
▸ PABPC1 P11940 1/20 0.57
▸ RECQL P46063 1/20 0.57
▸ RAB9A P51151 1/20 0.57
▸ SMN1; SMN2 Q16637 1/20 0.57
▸ USP2 O75604 1/20 0.50
▸ POLB P06746 1/20 0.50
▸ MAPT P10636 1/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ ATM Q13315 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2671337 0.98 STAT3 (0.67) STAT3HIF1ATERTMEN1RGS12
SCHEMBL29384023 0.98 STAT3 (0.67) STAT3HIF1ATERTMEN1RGS12
SCHEMBL7485132 0.97 STAT3 (0.65) STAT3HIF1ATERTMEN1RGS12
SCHEMBL1105114 0.97 STAT3 (0.65) STAT3HIF1ATERTMEN1RGS12
SCHEMBL6263953 0.97 STAT3 (0.65) STAT3HIF1ATERTMEN1RGS12
SCHEMBL418871 0.97 STAT3 (0.65) STAT3HIF1ATERTMEN1RGS12
SCHEMBL284967 0.97 STAT3 (0.65) STAT3HIF1ATERTMEN1RGS12
SCHEMBL18379137 0.97 STAT3 (0.65) STAT3HIF1ATERTMEN1RGS12
SCHEMBL8071104 0.97 STAT3 (0.65) STAT3HIF1ATERTMEN1RGS12
SCHEMBL18376159 0.97 STAT3 (0.65) STAT3HIF1ATERTMEN1RGS12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7459256-B2 Image forming method and image forming apparatus KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-12-02 — — US disclosed
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