Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4862599 | 0.99 | TDP1 (0.46) | TDP1ACHECYP11B1CYP11B2CYP19A1 | |
| SCHEMBL13987266 | 0.99 | TDP1 (0.47) | TDP1ACHECYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL4860034 | 0.98 | TDP1 (0.46) | TDP1ACHECYP11B1CYP11B2CYP19A1 | |
| SCHEMBL13987647 | 0.86 | CHRM2 (0.52) | TDP1ACHETP53 | |
| SCHEMBL13987277 | 0.85 | TDP1 (0.48) | TDP1ACHECYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL4860785 | 0.85 | CHRM2 (0.51) | TDP1ACHE | |
| Hydrochloric Acid SCHEMBL4861561 | 0.85 | TDP1 (0.47) | TDP1ACHECYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL4855144 | 0.84 | CHRM2 (0.49) | TDP1ACHE | |
| SCHEMBL13987242 | 0.84 | TDP1 (0.49) | TDP1ACHECYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL4858964 | 0.84 | TDP1 (0.48) | TDP1ACHECYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |