Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398823 | 0.91 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL1398706 | 0.91 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL1398855 | 0.89 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL8054496 | 0.85 | HCRTR1 (0.66) | HCRTR1HCRTR2 | |
| SCHEMBL1398843 | 0.85 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL1398699 | 0.84 | HCRTR1 (0.62) | HCRTR1HCRTR2 | |
| SCHEMBL1398680 | 0.82 | HCRTR1 (0.56) | HCRTR1HCRTR2 | |
| SCHEMBL1398681 | 0.82 | HCRTR1 (0.56) | HCRTR1HCRTR2 | |
| SCHEMBL27774032 | 0.81 | HCRTR1 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL1398674 | 0.79 | HCRTR1 (0.64) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069332-B1 | AZETIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-03-02 | — | — | EP | disclosed |