Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14189198 | 0.90 | USP2 (0.68) | TSHRUSP2MAPTLMNANPSR1 | |
| SCHEMBL13991652 | 0.85 | HTT (0.60) | TSHRUSP2MAPTLMNANPSR1 | |
| SCHEMBL19021801 | 0.85 | USP2 (0.62) | TSHRUSP2MAPTLMNANPSR1 | |
| SCHEMBL12133451 | 0.83 | USP2 (0.60) | TSHRUSP2MAPTLMNANPSR1 | |
| SCHEMBL17212342 | 0.83 | ATM (0.61) | TSHRUSP2MAPTLMNANPSR1 | |
| SCHEMBL10313439 | 0.81 | USP2 (0.58) | TSHRUSP2MAPTLMNANPSR1 | |
| SCHEMBL12881505 | 0.81 | USP2 (0.58) | TSHRUSP2MAPTLMNANPSR1 | |
| SCHEMBL16348229 | 0.81 | TSHR (0.62) | TSHRUSP2MAPTLMNANPSR1 | |
| SCHEMBL14934283 | 0.81 | TSHR (0.62) | TSHRUSP2MAPTLMNANPSR1 | |
| SCHEMBL4294603 | 0.81 | TSHR (0.54) | TSHRUSP2LMNAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8727775-B2 | Dimer acid-derived dimethacrylates and use in dental restorative compositions | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2014-05-20 | — | — | US | disclosed |
| US-20080318188-A1 | Dimer Acid-Derived Dimethacrylates and Use in Dental Restorative Compositions | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318188-A1 | Dimer Acid-Derived Dimethacrylates and Use in Dental Restorative Compositions | GRM7, NR2C2, GRM8 | TSHR 988/4885USP2 2347/4885MAPT 3085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.