Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 17/20 | 0.73 |
| ▸ | KDR | P35968 | 14/20 | 0.73 |
| ▸ | KIT | P10721 | 3/20 | 0.69 |
| ▸ | MET | P08581 | 2/20 | 0.69 |
| ▸ | AXL | P30530 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1878013 | 0.92 | PDGFRA (0.82) | PDGFRAKDRKITMETAXL | |
| SCHEMBL1878889 | 0.92 | PDGFRA (0.73) | PDGFRAKDRKITMET | |
| SCHEMBL1877226 | 0.90 | PDGFRA (0.84) | PDGFRAKDRKITMET | |
| SCHEMBL13992603 | 0.88 | PDGFRA (0.63) | PDGFRAKDRKITMET | |
| SCHEMBL1878386 | 0.87 | PDGFRA (0.92) | PDGFRAKDRKITAXL | |
| SCHEMBL1879986 | 0.86 | PDGFRA (0.80) | PDGFRAKDRKITMETAXL | |
| SCHEMBL1881332 | 0.85 | PDGFRA (0.92) | PDGFRAKDRKITAXL | |
| SCHEMBL1878994 | 0.85 | PDGFRA (0.77) | PDGFRAKDRKITAXL | |
| SCHEMBL5824578 | 0.85 | PDGFRA (0.67) | PDGFRAKDRKITMETAXL | |
| SCHEMBL7490931 | 0.85 | PDGFRA (1.00) | PDGFRAKDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312221-A1 | QUINOLINE DERIVATIVE AND QUINAZOLINE DERIVATIVE INHIBITING SELF-PHOSPHORYLATION OF HEPATOCYTUS PROLIFERATOR RECEPTOR, AND MEDICINAL COMPOSITION CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2008-12-18 | — | — | US | disclosed |
| US-20080312221-A1 | QUINOLINE DERIVATIVE AND QUINAZOLINE DERIVATIVE INHIBITING SELF-PHOSPHORYLATION OF HEPATOCYTUS PROLIFERATOR RECEPTOR, AND MEDICINAL COMPOSITION CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312221-A1 | QUINOLINE DERIVATIVE AND QUINAZOLINE DERIVATIVE INHIBITING SELF-PHOSPHORYLATION OF HEPATOCYTUS PROLIFERATOR RECEPTOR, AND MEDICINAL COMPOSITION CONTAINING THE SAME | NR1H2, NR1H3, NR1H4 | PDGFRA 1825/4885KDR 3100/4885KIT 4153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.