Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 10/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.45 |
| ▸ | TUBB | P07437 | 3/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 5/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1399305 | 0.86 | HTR2A (0.59) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399214 | 0.86 | IDO1 (0.46) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399345 | 0.84 | HTR2A (0.50) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399358 | 0.82 | HTR2A (0.50) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399252 | 0.80 | IDO1 (0.48) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399242 | 0.78 | HTR2A (0.60) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399299 | 0.78 | HTR2A (0.60) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399292 | 0.78 | IDO1 (0.47) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399487 | 0.77 | HTR2A (0.65) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399283 | 0.77 | HTR2A (0.56) | IDO1HTR2ATRPM8HTR1DCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860100-B1 | 2-(1H-indolylsulfanyl)-benzyl amine derivatives as SSRI | LUNDBECK & CO AS H (DK) | 2011-03-02 | — | — | EP | claimed |