Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13993617 | 0.86 | CD38 (0.46) | CD38SMYD3 | |
| SCHEMBL13993601 | 0.83 | CD38 (0.45) | CD38 | |
| SCHEMBL954572 | 0.79 | CD38 (0.41) | CD38SMYD3 | |
| SCHEMBL4288266 | 0.79 | NPC1 (0.49) | — | |
| SCHEMBL13993729 | 0.79 | CD38 (0.36) | CD38 | |
| SCHEMBL13993613 | 0.78 | CDK5 (0.46) | CD38 | |
| SCHEMBL13993724 | 0.77 | CCNA2 (0.41) | CD38 | |
| SCHEMBL13993731 | 0.76 | STAT3 (0.42) | CD38 | |
| SCHEMBL13993713 | 0.75 | CDK2 (0.48) | — | |
| SCHEMBL8263073 | 0.75 | CDK14 (0.41) | CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306069-A1 | Pyrazole Derivatives for the Inhibition of CDK'S and GSK'S | ASTEX THERAPEUTICS LIMITED (UK) | 2008-12-11 | — | — | US | disclosed |
| US-20080306069-A1 | Pyrazole Derivatives for the Inhibition of CDK'S and GSK'S | ASTEX THERAPEUTICS LIMITED (UK) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306069-A1 | Pyrazole Derivatives for the Inhibition of CDK'S and GSK'S | GSK3A, CDK11A, CDK1 | CD38 3636/4885SMYD3 1142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.