Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 19/20 | 0.46 |
| ▸ | CDK9 | P50750 | 19/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5004997 | 0.96 | CCNT1 (0.51) | CCNT1CDK9 | |
| SCHEMBL5001500 | 0.94 | CCNT1 (0.49) | CCNT1CDK9 | |
| SCHEMBL5005884 | 0.93 | CCNT1 (0.42) | CCNT1CDK9BTK | |
| SCHEMBL5004837 | 0.93 | CCNT1 (0.40) | CCNT1CDK9 | |
| SCHEMBL5010289 | 0.92 | CCNT1 (0.41) | CCNT1CDK9 | |
| SCHEMBL5004741 | 0.92 | CCNT1 (0.41) | CCNT1CDK9 | |
| SCHEMBL5001673 | 0.91 | NAMPT (0.42) | CCNT1CDK9BTK | |
| SCHEMBL5001665 | 0.91 | KIT (0.45) | CCNT1CDK9BTK | |
| SCHEMBL5010222 | 0.90 | CCNT1 (0.44) | CCNT1CDK9BTK | |
| SCHEMBL5004902 | 0.90 | CCNT1 (0.40) | CCNT1CDK9BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465726-B2 | Substituted pyrrolo[2.3-B]pyridines | OSI PHARMACEUTICALS, INC. (US) | 2008-12-16 | — | — | US | disclosed |
| US-7465726-B2 | Substituted pyrrolo[2.3-B]pyridines | OSI PHARMACEUTICALS, INC. (US) | 2008-12-16 | — | — | US | disclosed |