Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 4/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10343084 | 1.00 | SLC18A3 (0.48) | SLC18A3SIGMAR1GRIN2BGAAMAPT | |
| SCHEMBL10343264 | 0.88 | NPC1 (0.54) | SLC18A3SIGMAR1GRIN2BMAPTCYP2D6 | |
| SCHEMBL10343265 | 0.88 | NPC1 (0.54) | SLC18A3SIGMAR1GRIN2BMAPTCYP2D6 | |
| SCHEMBL10177659 | 0.88 | AKR1C3 (0.47) | SLC18A3SIGMAR1GRIN2BGAAMAPT | |
| SCHEMBL7733705 | 0.84 | KDM4E (0.39) | SLC18A3SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL7733708 | 0.84 | KDM4E (0.39) | SLC18A3SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL30909 | 0.83 | ESR2 (0.41) | GAAMAPTCYP2D6KMT2ASMN1; SMN2 | |
| SCHEMBL11027831 | 0.81 | AKR1C3 (0.42) | SLC18A3SIGMAR1GRIN2BGAAMAPT | |
| SCHEMBL11031012 | 0.81 | AKR1C3 (0.42) | SLC18A3SIGMAR1GRIN2BGAAMAPT | |
| SCHEMBL41763 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |
| CN-110563631-B | IDO inhibiting compound and application thereof | 爱斯特（成都）生物制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110563631-A | compound for inhibiting IDO and application thereof | 爱斯特（成都）生物制药股份有限公司 | 2019-12-13 | — | — | CN | disclosed |
| CN-103003266-A | Hydroxyalkylbenzylpyrazoles and their use for the treatment of hyperproliferative and angiogenic diseases | BAYER IP GMBH | 2013-03-27 | — | — | CN | disclosed |
| CN-102282143-A | Heterocyclically substituted aryl compounds and application thereof | — | 2011-12-14 | — | — | CN | disclosed |
| US-7914707-B2 | Additive for non-aqueous electrolyte and secondary battery using the same | LG CHEM, LTD. (KR) | 2011-03-29 | — | — | US | disclosed |
| US-7914707-B2 | Additive for non-aqueous electrolyte and secondary battery using the same | LG CHEM, LTD. (KR) | 2011-03-29 | — | — | US | disclosed |
| US-7914707-B2 | Additive for non-aqueous electrolyte and secondary battery using the same | LG CHEM, LTD. (KR) | 2011-03-29 | — | — | US | disclosed |
| EP-0259346-B1 | R-1-CYAN-1-R2 -CIS-4-R1 -CYCLOHEXANE COMPOUNDS | MERCK PATENT GmbH (DE) | 1990-04-04 | — | — | EP | disclosed |
| US-4886620-A | Smectic liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-12-12 | — | — | US | disclosed |
| EP-0335579-A2 | Photo-recording media and photo-recording method | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-10-04 | — | — | EP | disclosed |
| EP-0259346-A1 | r-1-CYAN-1-R2 -CIS-4-R1 -CYCLOHEXANE COMPOUNDS. | MERCK PATENT GMBH (DE) | 1988-03-16 | — | — | EP | disclosed |
| WO-1987005618-A1 | r-1-CYAN-1-R2-CIS-4-R1-CYCLOHEXANE COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-09-24 | — | — | WO | disclosed |
| EP-0233267-A1 | SMECTIC CRYSTAL PHASES. | MERCK PATENT GMBH (DE) | 1987-08-26 | — | — | EP | disclosed |
| WO-1987001717-A2 | SMECTIC CYSTAL PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-03-26 | — | — | WO | disclosed |
| EP-0154849-A2 | Cyclohexane derivatives | MERCK PATENT GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |
| EP-0051768-A1 | Liquid crystal indicator device | SIEMENS AKTIENGESELLSCHAFT (DE) | 1982-05-19 | — | — | EP | disclosed |
| US-4130502-A | Liquid crystalline cyclohexane derivatives | MERCK PATENT GESELLSCHAFT MIT (DE) | 1978-12-19 | — | — | US | disclosed |