Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 12/20 | 0.62 |
| ▸ | CDK2 | P24941 | 9/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13998494 | 0.87 | GSK3B (0.71) | GSK3BCDK2CCNE1 | |
| SCHEMBL13998461 | 0.87 | GSK3B (0.82) | GSK3BCDK2CCNE1 | |
| SCHEMBL13998513 | 0.87 | GSK3B (0.59) | GSK3BCDK2CCNE1 | |
| SCHEMBL13998482 | 0.84 | GSK3B (0.68) | GSK3BCDK2CCNE1 | |
| SCHEMBL13309452 | 0.84 | GSK3B (0.61) | GSK3BCDK2CCNE1 | |
| SCHEMBL13998472 | 0.83 | GSK3B (0.60) | GSK3BCDK2CCNE1 | |
| SCHEMBL12952881 | 0.82 | GSK3B (0.79) | GSK3BCDK2CCNE1 | |
| SCHEMBL13998521 | 0.80 | GSK3B (0.70) | GSK3BCDK2CCNE1 | |
| SCHEMBL13998503 | 0.79 | GSK3B (0.70) | GSK3BCDK2CCNE1 | |
| SCHEMBL13998583 | 0.78 | GSK3B (0.49) | GSK3BCDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470695-B2 | N-heteroaryl pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPORATION (US) | 2008-12-30 | — | — | US | disclosed |
| US-7470695-B2 | N-heteroaryl pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPORATION (US) | 2008-12-30 | — | — | US | disclosed |
| EP-1534709-B1 | PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORP (US) | 2007-06-13 | — | — | EP | disclosed |
| WO-2007044401-A2 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |
| US-7196092-B2 | N-heteroaryl pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPORATION (US) | 2007-03-27 | — | — | US | disclosed |
| US-7196092-B2 | N-heteroaryl pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPORATION (US) | 2007-03-27 | — | — | US | disclosed |