SCHEMBL1399991

SCHEMBL1399991

C1=CCC2C(=C1)C=C1NCCCC12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5242459 0.77
Hydrochloric Acid SCHEMBL29935533 0.76
SCHEMBL4706659 0.74
SCHEMBL743262 0.74
SCHEMBL1721252 0.73
SCHEMBL28347353 0.73
SCHEMBL1721292 0.72
SCHEMBL11765618 0.71
Methylamine SCHEMBL8761530 0.70
SCHEMBL28169170 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2496559-B1 ARYL- AND HETEROARYLCARBONYL DERIVATIVES OF HEXAHYDROINDENOPYRIDINE AND OCTAHYDROBENZOQUINOLINE AND THEIR USE AS HSD 1 INHIBITORS VITAE PHARMACEUTICALS INC (US) 2018-01-10 EP disclosed
US-9663470-B2 Aryl- and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline VITAE PHARMACEUTICALS, INC. (US) 2017-05-30 US disclosed
US-9663470-B2 Aryl- and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline VITAE PHARMACEUTICALS, INC. (US) 2017-05-30 US disclosed
US-20160272590-A1 ARYL- AND HETEROARYLCARBONYL DERIVATIVES OF HEXAHYDROINDENOPYRIDINE AND OCTAHYDROBENZOQUINOLINE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2016-09-22 US disclosed
US-9328072-B2 Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline VITAE PHARMACEUTICALS, INC. (US) 2016-05-03 US disclosed
US-9328072-B2 Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline VITAE PHARMACEUTICALS, INC. (US) 2016-05-03 US disclosed
CN-105037326-A Aryl- and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline VITAE PHARMACEUTICALS INC 2015-11-11 CN disclosed
US-9120769-B2 Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline BOEHRINGER-INGELHEIM INTERNATIONAL GMBH (DE) 2015-09-01 US disclosed
US-9120769-B2 Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline BOEHRINGER-INGELHEIM INTERNATIONAL GMBH (DE) 2015-09-01 US disclosed
CN-102666491-B Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline VITAE PHARMACEUTICALS INC 2015-06-24 CN disclosed
US-5952336-A ANTIFERTILITY AGENTS, CONTRACEPTIVES RESEARCH TRIANGLE INSTITUTE (US) 1999-09-14 US disclosed
WO-1998033525-A1 HEXAHYDROINDENOPYRIDINE COMPOUNDS HAVING ANTISPERMATOGENIC ACTIVITY RESEARCH TRIANGLE INSTITUTE (US) 1998-08-06 WO disclosed
WO-1998033525-A1 HEXAHYDROINDENOPYRIDINE COMPOUNDS HAVING ANTISPERMATOGENIC ACTIVITY RESEARCH TRIANGLE INSTITUTE (US) 1998-08-06 WO disclosed
EP-0505510-A4 ANTIPSYCHOTIC HEXAHYDRO-2-I(H)-INDENO 1,2-C)PYRIDINE DERIVATIVES MCNEILAB INC (US) 1994-08-10 EP disclosed
US-5319084-A Orally active male contraceptive with limited side effects RESEARCH TRIANGLE INSTITUTE (US) 1994-06-07 US disclosed
US-5319084-A Orally active male contraceptive with limited side effects RESEARCH TRIANGLE INSTITUTE (US) 1994-06-07 US disclosed
US-5319084-A Orally active male contraceptive with limited side effects RESEARCH TRIANGLE INSTITUTE (US) 1994-06-07 US disclosed
EP-0505510-A1 ANTIPSYCHOTIC HEXAHYDRO-2$i(H)-INDENO 1,2-c]PYRIDINE DERIVATIVES MCNEILAB, INC. (US) 1992-09-30 EP disclosed
US-5075315-A Dopamine, serotonin antagonists MCNEILAB, INC. (US) 1991-12-24 US disclosed
WO-1991017992-A1 ANTIPSYCHOTIC HEXAHYDRO-2H-INDENO[1,2-c]PYRIDINE DERIVATIVES MCNEILAB INC. (US) 1991-11-28 WO disclosed