⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5030457 | 0.79 | LATS1 (0.32) | — | |
| SCHEMBL5031347 | 0.77 | BRD4 (0.40) | — | |
| SCHEMBL1490507 | 0.75 | BRD4 (0.43) | — | |
| SCHEMBL5339810 | 0.73 | ADORA2A (0.39) | — | |
| SCHEMBL5336992 | 0.67 | KDM4E (0.32) | — | |
| SCHEMBL5030370 | 0.66 | GAA (0.31) | — | |
| SCHEMBL5027830 | 0.65 | BRD4 (0.31) | — | |
| SCHEMBL5030399 | 0.63 | BRD4 (0.38) | — | |
| SCHEMBL22642826 | 0.61 | TDP1 (0.34) | — | |
| SCHEMBL22131136 | 0.61 | MAPK10 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312434-A1 | PROCESS FOR IMIDAZO [4,5-C] PYRIDIN-4-AMINES | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2008-12-18 | — | — | US | disclosed |