Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PTPN22 | Q9Y2R2 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | IL6 | P05231 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13980691 | 0.93 | CDC25B (0.60) | CDC25BMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL14001193 | 0.92 | CSNK2A2 (0.56) | CDC25BMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL14001085 | 0.91 | CDC25B (0.67) | CDC25BMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL13980687 | 0.89 | CDC25B (0.60) | CDC25BMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL14001186 | 0.88 | CDC25B (0.68) | CDC25BMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL4667576 | 0.87 | CDC25B (0.81) | CDC25BMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL4667578 | 0.87 | CDC25B (0.81) | CDC25BMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL14001099 | 0.84 | CDC25B (0.71) | CDC25BMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL13980706 | 0.84 | MEN1 (0.60) | CDC25BMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL14001156 | 0.82 | CSNK2A2 (0.72) | CDC25BMEN1KMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149311-A1 | USE OF DERIVATIVES OF 3-OXO-2,3-DIHYDRO-5H-THIAZOLOF[3,2-A]PYRIMIDINE OR OF 3-OXO-2,3-DIHYDRO-5H-SELENAZOLO[3,2-A]PYRIMIDINE OR OF 3-OXO-1,2,3-TRIHYDRO-5H-IMIDAZOLO[1,2-A]PYRIMIDINE FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS INTENDED FOR THE TREATMENT OF CANCER | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2008-12-11 | — | — | WO | disclosed |