Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13871722 | 0.86 | CNR2 (0.47) | CNR2LMNAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL2716575 | 0.85 | CNR2 (0.46) | CNR2LMNAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL13871367 | 0.83 | CNR2 (0.45) | CNR2LMNAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL13871388 | 0.83 | CNR2 (0.60) | CNR2LMNAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL13871503 | 0.82 | CNR2 (0.44) | CNR2LMNAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL13871504 | 0.82 | CNR2 (0.44) | CNR2LMNAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL13871509 | 0.82 | CNR2 (0.44) | CNR2LMNAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL13871341 | 0.82 | CNR2 (0.43) | CNR2LMNAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL14003015 | 0.82 | CNR2 (0.53) | CNR2ALDH1A1SMN1; SMN2CNR1NPC1 | |
| SCHEMBL13871360 | 0.82 | CNR2 (0.43) | CNR2LMNAHPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7452997-B2 | Tetrahydro-indazole cannabinoid modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-11-18 | — | — | US | disclosed |
| US-7452997-B2 | Tetrahydro-indazole cannabinoid modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-11-18 | — | — | US | disclosed |