Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 8/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4832107 | 0.90 | CNR1 (0.46) | CNR1USP2HIF1AALDH1A1CASP1 | |
| SCHEMBL14003384 | 0.88 | KMT2A (0.43) | CNR1USP2HIF1AALDH1A1CASP1 | |
| SCHEMBL4832103 | 0.83 | KMT2A (0.44) | SLC2A1CNR1USP2HIF1AALDH1A1 | |
| SCHEMBL4836604 | 0.81 | CNR1 (0.48) | CNR1LMNANR1H2NR1H3CYP3A4 | |
| SCHEMBL4836266 | 0.81 | CNR1 (0.57) | CNR1LMNAMAPTCYP3A4CYP2C9 | |
| SCHEMBL4841662 | 0.81 | CNR1 (0.50) | CNR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13114659 | 0.79 | CNR1 (0.51) | SLC2A1CNR1USP2HIF1AALDH1A1 | |
| SCHEMBL4836219 | 0.79 | CNR1 (0.49) | CNR1NR1H2NR1H3CYP3A4CYP2C9 | |
| SCHEMBL14003386 | 0.78 | POLB (0.42) | CNR1USP2HIF1AALDH1A1CASP1 | |
| SCHEMBL4841651 | 0.78 | CNR1 (0.45) | CNR1ALDH1A1LMNANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7452892-B2 | Triazolopyrimidine cannabinoid receptor 1 antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-18 | — | — | US | disclosed |
| US-7452892-B2 | Triazolopyrimidine cannabinoid receptor 1 antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-18 | — | — | US | disclosed |