Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.75 |
| ▸ | PPARD | Q03181 | 16/20 | 0.75 |
| ▸ | PPARG | P37231 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1400281 | 0.98 | PPARA (0.71) | PPARAPPARDPPARG | |
| SCHEMBL1400506 | 0.90 | PPARA (0.74) | PPARAPPARDPPARG | |
| SCHEMBL3023128 | 0.86 | PPARD (1.00) | PPARAPPARD | |
| SCHEMBL3019658 | 0.85 | PPARA (0.76) | PPARAPPARDPPARG | |
| SCHEMBL1400588 | 0.83 | PPARD (0.95) | PPARAPPARD | |
| SCHEMBL1400389 | 0.83 | PPARA (0.62) | PPARAPPARDPPARG | |
| SCHEMBL12798704 | 0.82 | PPARD (0.85) | PPARAPPARD | |
| SCHEMBL3120428 | 0.81 | PPARD (1.00) | PPARAPPARD | |
| SCHEMBL12798534 | 0.80 | PPARD (0.81) | PPARAPPARD | |
| SCHEMBL1400545 | 0.80 | PPARA (0.72) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578715-B1 | INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION | BAYER PHARMACEUTICALS CORP (US) | 2011-03-02 | — | — | EP | disclosed |