Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSH | P09668 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CASP14 | P31944 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.38 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14005870 | 0.96 | CNR2 (0.51) | CNR2PRKDCEGFRCHRNB4CHRNA3 | |
| SCHEMBL14005907 | 0.91 | CNR2 (0.58) | CNR2PRKDCEGFROPRL1CYP1A2 | |
| Acetic Acid SCHEMBL4649738 | 0.89 | CNR2 (0.52) | CNR2PRKDCEGFRPDCD1CD274 | |
| SCHEMBL14006027 | 0.89 | CNR2 (0.48) | CNR2PRKDCEGFRCHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL4648739 | 0.88 | CNR2 (0.47) | CNR2PRKDCEGFRCHRNB4CHRNA3 | |
| SCHEMBL4649078 | 0.85 | CNR2 (0.57) | CNR2PRKDCCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL14005878 | 0.85 | CNR2 (0.49) | CNR2PRKDCEGFRCHRNB4CHRNA3 | |
| Acetic Acid SCHEMBL4649700 | 0.85 | CNR2 (0.59) | CNR2PDCD1CD274CYP1A2CYP2D6 | |
| SCHEMBL14006024 | 0.83 | CNR2 (0.57) | CNR2PRKDCCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4649605 | 0.83 | CNR2 (0.56) | CNR2PRKDCEGFRCHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280868-A1 | Pyridine Derivatives and Their Use as Cb2 Receptor Modulators | GLAXO GROUP LIMITED (GB) | 2008-11-13 | — | — | US | disclosed |
| US-20080280868-A1 | Pyridine Derivatives and Their Use as Cb2 Receptor Modulators | GLAXO GROUP LIMITED (GB) | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280868-A1 | Pyridine Derivatives and Their Use as Cb2 Receptor Modulators | CNR2, CNR1, TRPV1 | CNR2 1/4885PRKDC 4152/4885EGFR 818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.