Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.61 |
| ▸ | PPARA | Q07869 | 14/20 | 0.61 |
| ▸ | PPARD | Q03181 | 6/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401146 | 1.00 | PPARG (0.61) | PPARGPPARAPPARD | |
| SCHEMBL3023167 | 0.83 | PPARD (0.66) | PPARGPPARAPPARD | |
| SCHEMBL1400658 | 0.82 | PPARA (0.69) | PPARGPPARAPPARD | |
| SCHEMBL1400457 | 0.79 | PPARA (0.73) | PPARGPPARAPPARD | |
| SCHEMBL1400640 | 0.79 | PPARA (0.70) | PPARGPPARAPPARD | |
| SCHEMBL3018542 | 0.79 | PPARA (0.69) | PPARGPPARAPPARD | |
| SCHEMBL1400650 | 0.79 | PPARA (0.61) | PPARGPPARAPPARD | |
| SCHEMBL1400600 | 0.78 | PPARA (0.68) | PPARGPPARAPPARD | |
| SCHEMBL3023727 | 0.78 | PPARA (0.68) | PPARGPPARAPPARD | |
| SCHEMBL1400716 | 0.78 | PPARA (0.67) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578715-B1 | INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION | BAYER PHARMACEUTICALS CORP (US) | 2011-03-02 | — | — | EP | disclosed |