Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12570786 | 0.90 | PTGDR (0.44) | PTGDR2PTGDRALDH1A1MAPTHPGD | |
| SCHEMBL12570787 | 0.84 | PTGDR2 (0.46) | PTGDR2PTGDRKDM4EMEN1ALDH1A1 | |
| SCHEMBL2004148 | 0.77 | PTGDR2 (0.82) | PTGDR2PTGDRCYP3A4 | |
| SCHEMBL12570797 | 0.75 | CYP3A4 (0.60) | PTGDR2PTGDRKDM4EMEN1ALDH1A1 | |
| SCHEMBL2000414 | 0.71 | PTGDR (0.46) | PTGDR2PTGDRKDM4EMEN1ALDH1A1 | |
| SCHEMBL2005251 | 0.70 | PTGDR (0.55) | PTGDR2PTGDRKDM4EMEN1ALDH1A1 | |
| SCHEMBL12570789 | 0.69 | PTGDR2 (0.74) | PTGDR2PTGDRCYP3A4PPARG | |
| SCHEMBL13742647 | 0.68 | SRD5A2 (0.52) | PTGDR2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL1036212 | 0.67 | GAA (0.68) | KDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL2002117 | 0.66 | CYP3A4 (0.52) | PTGDR2PTGDRKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137027-A2 | COMPOUNDS AS CRTH2 AND/OR PGD2 RECEPTORS MODULATORS AND THEIR USE FOR TREATING ASTHMA AND ALLERGIC INFLAMMATION | AMGEN INC. (US) | 2008-11-13 | — | — | WO | disclosed |