Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 17/20 | 0.48 |
| ▸ | GAA | P10253 | 16/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2249754 | 0.88 | GAA (0.49) | MAPTGAATDP1MAPK1MEN1 | |
| SCHEMBL2250466 | 0.84 | GAA (0.69) | MAPTGAATDP1MAPK1MEN1 | |
| SCHEMBL12360744 | 0.83 | GAA (0.48) | MAPTGAATDP1MAPK1MEN1 | |
| SCHEMBL12376237 | 0.81 | MAPT (0.45) | MAPTGAATDP1MAPK1MEN1 | |
| SCHEMBL2249818 | 0.81 | MAPT (0.54) | MAPTGAATDP1MEN1KMT2A | |
| SCHEMBL12360742 | 0.80 | MAPT (0.51) | MAPTGAATDP1MAPK1MEN1 | |
| SCHEMBL2250617 | 0.79 | MAPT (0.67) | MAPTGAATDP1MEN1KMT2A | |
| SCHEMBL2253789 | 0.78 | GAA (0.53) | MAPTGAATDP1MAPK1MEN1 | |
| SCHEMBL2258207 | 0.78 | MAPT (0.51) | MAPTGAATDP1MEN1KMT2A | |
| SCHEMBL12360669 | 0.78 | GAA (0.53) | MAPTGAATDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141249-A1 | IMIDAZOL (1,2-A)PYRIDINES AND RELATED COMPOUNDS WITH ACTIVITY AT CANNABINOID CB2 RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2008-11-20 | — | — | WO | disclosed |