Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6914864 | 1.00 | POLB (0.43) | POLBALDH1A1TDP1KDM4ELMNA | |
| SCHEMBL264855 | 1.00 | POLB (0.43) | POLBALDH1A1TDP1KDM4ELMNA | |
| SCHEMBL2916591 | 1.00 | POLB (0.43) | POLBALDH1A1TDP1KDM4ELMNA | |
| SCHEMBL6914871 | 1.00 | POLB (0.43) | POLBALDH1A1TDP1KDM4ELMNA | |
| SCHEMBL10146298 | 1.00 | POLB (0.43) | POLBALDH1A1TDP1KDM4ELMNA | |
| SCHEMBL11792802 | 0.84 | POLB (0.32) | POLBALDH1A1TDP1KDM4EGAA | |
| SCHEMBL10739509 | 0.83 | POLB (0.54) | POLBALDH1A1TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL60588 | 0.83 | POLB (0.54) | POLBALDH1A1TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL31737192 | 0.83 | POLB (0.54) | POLBALDH1A1TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL10739512 | 0.83 | POLB (0.54) | POLBALDH1A1TDP1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995240-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-11-26 | — | — | EP | disclosed |