Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 17/20 | 0.37 |
| ▸ | PPARA | Q07869 | 5/20 | 0.37 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654150 | 0.92 | PTGDR2 (0.46) | PTGDR2PPARDPPARAPPARG | |
| SCHEMBL14017076 | 0.88 | PPARD (0.40) | PTGDR2PPARDPPARAPPARGMRGPRX4 | |
| SCHEMBL4654025 | 0.85 | PPARD (0.52) | PPARDPPARAPPARG | |
| SCHEMBL4654024 | 0.84 | PPARD (0.47) | PTGDR2PPARDPPARAPPARG | |
| SCHEMBL14016243 | 0.82 | PPARD (0.42) | PPARDPPARAPPARG | |
| SCHEMBL14449268 | 0.81 | PPARD (0.41) | PTGDR2PPARDPPARAPPARG | |
| SCHEMBL4654136 | 0.79 | PPARD (0.47) | PTGDR2PPARDPPARAPPARG | |
| SCHEMBL5157725 | 0.77 | PPARD (0.47) | PPARDPPARAPPARG | |
| SCHEMBL4654002 | 0.76 | PPARD (0.46) | PTGDR2PPARDPPARAPPARG | |
| SCHEMBL14017062 | 0.76 | PPARD (0.41) | PTGDR2PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740568-B1 | BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES USEFUL FOR THE TREATMENT OF CARDIOVASCULAR DISEASE. | SMITHKLINE BEECHAM CORP (US) | 2008-11-26 | — | — | EP | disclosed |