⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8259989 | 0.82 | — | — | |
| SCHEMBL22856027 | 0.80 | — | — | |
| SCHEMBL19187314 | 0.80 | — | — | |
| SCHEMBL19906556 | 0.79 | — | — | |
| SCHEMBL13679345 | 0.78 | — | — | |
| SCHEMBL18569746 | 0.78 | — | — | |
| SCHEMBL18698885 | 0.78 | — | — | |
| SCHEMBL14218079 | 0.78 | GRIK1 (0.31) | — | |
| SCHEMBL1911123 | 0.78 | — | — | |
| SCHEMBL13615493 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022101453-A1 | COMPOUNDS AND METHODS FOR TREATING A CYTOKINE-MEDIATED DISEASE | Conservatoire National des Arts et Métiers (FR) | 2022-05-19 | — | — | WO | disclosed |
| EP-3848375-A1 | METHODS OF PREPARING INTERMEDIATES FOR TOLL-LIKE RECEPTOR MODULATORS | Gilead Sciences, Inc. (US) | 2021-07-14 | — | — | EP | disclosed |
| EP-3461828-A2 | METHODS OF PREPARING TOLL-LIKE RECEPTOR MODULATORS | GILEAD SCIENCES, INC. (US) | 2019-04-03 | — | — | EP | disclosed |
| WO-2017191297-A1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | BCI PHARMA (FR) | 2017-11-09 | — | — | WO | disclosed |
| US-9573952-B2 | Methods of preparing toll-like receptor modulators | GILEAD SCIENCES, INC. (US) | 2017-02-21 | — | — | US | disclosed |
| EP-1703330-B1 | Plate-making method of negative-working lithographic printing plate precursor | FUJIFILM CORP (JP) | 2008-11-19 | — | — | EP | disclosed |
| WO-2008127399-A2 | AZAINDOLE DERIVATIVES AS CFTR MODULATORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-10-23 | — | — | WO | disclosed |