Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 18/20 | 0.52 |
| ▸ | MAPT | P10636 | 18/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2251728 | 0.88 | MAPT (0.68) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2251293 | 0.88 | MAPT (0.54) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2255497 | 0.86 | GAA (0.52) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL14016291 | 0.86 | MAPT (0.48) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2252122 | 0.85 | MAPT (0.56) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2251702 | 0.82 | GAA (0.47) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2252257 | 0.82 | GAA (0.51) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2254631 | 0.80 | MAPT (0.57) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2252550 | 0.80 | MAPT (0.53) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL13474713 | 0.79 | MAPT (0.50) | GAAMAPTKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141249-A1 | IMIDAZOL (1,2-A)PYRIDINES AND RELATED COMPOUNDS WITH ACTIVITY AT CANNABINOID CB2 RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2008-11-20 | — | — | WO | disclosed |