Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 18/20 | 0.57 |
| ▸ | MAPT | P10636 | 18/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14016086 | 0.92 | MAPT (0.58) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2257048 | 0.91 | GAA (0.47) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2250099 | 0.86 | MAPT (0.61) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2254414 | 0.84 | GAA (0.48) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL12360705 | 0.84 | GAA (0.48) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2254782 | 0.83 | GAA (0.48) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL12360704 | 0.83 | GAA (0.48) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2249448 | 0.83 | GAA (0.71) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2250548 | 0.83 | GAA (0.73) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2250617 | 0.82 | MAPT (0.67) | GAAMAPTKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141249-A1 | IMIDAZOL (1,2-A)PYRIDINES AND RELATED COMPOUNDS WITH ACTIVITY AT CANNABINOID CB2 RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2008-11-20 | — | — | WO | disclosed |