Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | HNF4A | P41235 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14017081 | 0.87 | MEN1 (0.45) | CYP19A1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL14016888 | 0.81 | CNR2 (0.34) | MEN1KMT2AALDH1A1KDM4ECNR2 | |
| SCHEMBL14017096 | 0.73 | CYP19A1 (0.32) | CYP19A1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL14017102 | 0.71 | CYP19A1 (0.38) | CYP19A1HNF4AMAPTMEN1KMT2A | |
| SCHEMBL14017031 | 0.70 | CNR2 (0.39) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL14016910 | 0.70 | AHR (0.34) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4624899 | 0.70 | NPC1 (0.38) | MAPTKDM4EALOX5SMN1; SMN2LMNA | |
| SCHEMBL13357807 | 0.68 | AHR (0.37) | HNF4AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL14016937 | 0.68 | KCNH2 (0.36) | HNF4AHSP90AA1MEN1KMT2AKDM4E | |
| SCHEMBL14017057 | 0.67 | TDP1 (0.32) | ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442825-B2 | Making nitrile compounds from ethylenically unsaturated compounds | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2008-10-28 | — | — | US | disclosed |
| US-7442825-B2 | Making nitrile compounds from ethylenically unsaturated compounds | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2008-10-28 | — | — | US | disclosed |