Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.52 |
| ▸ | RAMP1 | O60894 | 4/20 | 0.51 |
| ▸ | CALCA | P06881 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14016968 | 0.94 | CALCRL (0.58) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL14017256 | 0.93 | CALCRL (0.58) | CALCRLRAMP1CALCA | |
| SCHEMBL14017140 | 0.90 | CALCRL (0.53) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL14017143 | 0.89 | CALCRL (0.53) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL14375067 | 0.89 | CALCRL (0.57) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL14017324 | 0.88 | CALCRL (0.64) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL14017175 | 0.88 | CALCRL (0.54) | CALCRLRAMP1CALCA | |
| SCHEMBL14016881 | 0.88 | CALCRL (0.58) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL14016901 | 0.88 | CALCRL (0.55) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL14017097 | 0.88 | CALCRL (0.65) | CALCRLRAMP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439237-B2 | Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-21 | — | — | US | disclosed |