Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.59 |
| ▸ | RAMP1 | O60894 | 4/20 | 0.59 |
| ▸ | CALCA | P06881 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3311446 | 0.92 | CALCRL (0.69) | CALCRLRAMP1CALCA | |
| SCHEMBL3308468 | 0.87 | CALCRL (0.77) | CALCRLRAMP1CALCA | |
| SCHEMBL3308463 | 0.87 | CALCRL (0.77) | CALCRLRAMP1CALCA | |
| SCHEMBL14016906 | 0.82 | CALCRL (0.58) | CALCRLRAMP1CALCA | |
| SCHEMBL13331667 | 0.82 | CALCRL (0.70) | CALCRLRAMP1CALCA | |
| SCHEMBL14017265 | 0.82 | CALCRL (0.60) | CALCRLRAMP1CALCA | |
| SCHEMBL14017158 | 0.81 | CALCRL (0.56) | CALCRLRAMP1CALCA | |
| SCHEMBL13331986 | 0.80 | CALCRL (0.67) | CALCRLRAMP1CALCA | |
| SCHEMBL14017175 | 0.80 | CALCRL (0.54) | CALCRLRAMP1CALCA | |
| SCHEMBL3311450 | 0.80 | CALCRL (0.67) | CALCRLRAMP1CALCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439237-B2 | Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-21 | — | — | US | disclosed |