SCHEMBL1401723

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1401725	0.90	PIK3CD (0.48)	PIK3CDPIK3CAPIK3CBPIK3CGBRAF
	SCHEMBL1401697	0.90	PIK3CD (0.51)	PIK3CDPIK3CAPIK3CBPIK3CGKDR
	SCHEMBL662774	0.89	KDR (0.57)	PIK3CDPIK3CAPIK3CBPIK3CGBRAF
	SCHEMBL1401670	0.83	EGFR (0.56)	KDREGFRERBB2RIPK2RET
	SCHEMBL1401658	0.82	KDR (0.48)	BRAFKDREGFRERBB2RIPK2
	SCHEMBL1401676	0.80	KDR (0.48)	PIK3CDPIK3CAPIK3CBPIK3CGKDR
	SCHEMBL665930	0.80	BRAF (0.55)	PIK3CDPIK3CAPIK3CBPIK3CGBRAF
	SCHEMBL1401690	0.79	KDR (0.59)	PIK3CDPIK3CAPIK3CBPIK3CGBRAF
	SCHEMBL29111048	0.79	BRAF (0.55)	PIK3CDPIK3CAPIK3CBPIK3CGBRAF
	SCHEMBL12369330	0.78	EGFR (0.57)	PIK3CDPIK3CAPIK3CBPIK3CGKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.