Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24906 | 0.94 | — | — | |
| SCHEMBL16269701 | 0.94 | GABRR1 (0.42) | TSHRGABRR1GABBR2GABBR1ALDH1A1 | |
| SCHEMBL772924 | 0.94 | — | — | |
| SCHEMBL27292290 | 0.94 | GABRR1 (0.42) | TSHRGABRR1GABBR2GABBR1ALDH1A1 | |
| SCHEMBL428659 | 0.94 | — | — | |
| SCHEMBL8501200 | 0.91 | TSHR (0.50) | TSHRGABRR1GABBR2GABBR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9015216 | 0.90 | — | — | |
| Ammonia Solution, Strong SCHEMBL15129140 | 0.90 | — | — | |
| Methane SCHEMBL28148823 | 0.90 | — | — | |
| Water SCHEMBL28099735 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014168633-A1 | COMPOSITES FORMED FROM AN ABSORPTIVE FILLER AND A POLYURETHANE | BORAL IP HOLDINGS (AUSTRALIA) PTY LIMITED (AU) | 2014-10-16 | — | — | WO | claimed |
| US-12043694-B2 | Method for producing polyurethane hard foam composite elements using Mannich polyols | BASF SE (DE) | 2024-07-23 | — | — | US | disclosed |
| US-12037443-B2 | Polymeric materials with improved environmental durability | Westlake Royal Building Products Inc. (US) | 2024-07-16 | — | — | US | disclosed |
| US-12024583-B2 | Surfactant-free filled polyurethane foam and method of making same | Westlake Royal Building Products Inc. (US) | 2024-07-02 | — | — | US | disclosed |
| US-20240110037-A1 | BUILDING MATERIAL | RESHUFFLE CONSULTING, LLC | 2024-04-04 | — | — | US | disclosed |
| EP-3953406-B1 | POLYURETHANE AND PROCESS FOR MAKING | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-02-21 | — | — | EP | disclosed |
| US-20240001661-A1 | HIGHLY-FILLED POLYURETHANE COMPOSITES WITH FIBER REINFORCEMENT | Westlake Royal Building Products Inc. (US) | 2024-01-04 | — | — | US | disclosed |
| CN-113631607-B | Polyurethane and method for producing same | 陶氏环球技术有限责任公司 | 2023-10-27 | — | — | CN | disclosed |
| US-20230295370-A1 | FILLED POLYURETHANE OR POLYISOCYANURATE FOAM AND METHOD OF MAKING SAME | Westlake Royal Building Products Inc. (US) | 2023-09-21 | — | — | US | disclosed |
| EP-3728378-B1 | METHOD FOR THE PREPARATION OF POLYURETHANE HARD FOAM COMPOSITE ELEMENTS USING MANNICH POLYOLS | BASF SE (DE) | 2023-08-16 | — | — | EP | disclosed |
| EP-1423448-A4 | POLYMERIC URETHANE ESTER QUATS AND THEIR USE IN PERSONAL CARE COMPOSITIONS | ALZO INT INC (US) | 2005-06-29 | — | — | EP | disclosed |
| EP-1423448-A2 | POLYMERIC URETHANE ESTER QUATS AND THEIR USE IN PERSONAL CARE COMPOSITIONS | Alzo International, Inc. (US) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003016247-A2 | POLYMERIC URETHANE ESTER QUATS AND THEIR USE IN PERSONAL CARE COMPOSITIONS | ALZO INTERNATIONAL, INC. (US) | 2003-02-27 | — | — | WO | disclosed |
| EP-0352775-B1 | POLYOLS COMPRISING AN ALKOXYLATED MANNICH CONDENSATE AND PROCESS FOR PREPARING THE SAME | THE DOW CHEMICAL COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5120815-A | TERTIARY AMINE-CONTAINING POLYOLS PREPARED IN A MANNICH CONDENSATION REACTION USING A MIXTURE OF ALKANOLAMINES | THE DOW CHEMICAL COMPANY (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0405557-A2 | A process for preparing a mannich condensate polyether polyol and polyurethanes therefrom | THE DOW CHEMICAL COMPANY (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4939182-A | FLAME RETARDERS | THE DOW CHEMICAL COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0352776-A2 | Melamine-alkanolamine condensates, polyols and polyurethanes prepared therefrom and process for preparing the same | THE DOW CHEMICAL COMPANY (US) | 1990-01-31 | — | — | EP | disclosed |
| EP-0352775-A1 | Polyols comprising an alkoxylated mannich condensate and process for preparing the same | THE DOW CHEMICAL COMPANY (US) | 1990-01-31 | — | — | EP | disclosed |
| US-4883826-A | Tertiary amine-containing polyols prepared in a mannich condensation reaction using a mixture of alkanolamines | THE DOW CHEMICAL COMPANY (US) | 1989-11-28 | — | — | US | disclosed |