Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 8/20 | 0.54 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14018553 | 0.91 | NPY5R (0.55) | NPY5RUSP30CCR5MAP4K4MAPT | |
| SCHEMBL14332292 | 0.91 | NPY5R (0.51) | NPY5RUSP30CCR5MAP4K4MAPT | |
| SCHEMBL14332237 | 0.90 | NPY5R (0.54) | NPY5RUSP30CCR5MAPTWNT3A | |
| SCHEMBL14332109 | 0.90 | NPY5R (0.54) | NPY5RUSP30CCR5MAP4K4WNT3A | |
| SCHEMBL14332235 | 0.89 | NPY5R (0.54) | NPY5RUSP30CCR5MAP4K4WNT3A | |
| SCHEMBL14019250 | 0.89 | NPY5R (0.52) | NPY5RUSP30CCR5WNT3AGSK3B | |
| SCHEMBL14019249 | 0.89 | NPY5R (0.52) | NPY5RUSP30CCR5WNT3AGSK3B | |
| SCHEMBL14019170 | 0.89 | NPY5R (0.52) | NPY5RUSP30CCR5WNT3AGSK3B | |
| SCHEMBL14018579 | 0.88 | NPY5R (0.52) | NPY5RUSP30CCR5GSK3BDYRK1A | |
| SCHEMBL14332176 | 0.87 | NPY5R (0.51) | NPY5RUSP30CCR5WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343503-B1 | HETEROARYL UREA NEUROPEPTIDE Y Y5 RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2008-11-12 | — | — | EP | disclosed |
| US-7309704-B2 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-18 | — | — | US | disclosed |
| US-7309704-B2 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-18 | — | — | US | disclosed |