Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 14/20 | 0.72 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.72 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12046509 | 0.96 | KCNH2 (0.66) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL4300336 | 0.96 | KCNH2 (0.66) | KCNH2KCNQ1CACNA1C | |
| Fumaric Acid SCHEMBL4298944 | 0.92 | KCNH2 (0.61) | KCNH2KCNQ1CACNA1C | |
| Fumaric Acid SCHEMBL4301449 | 0.92 | KCNH2 (0.61) | KCNH2KCNQ1CACNA1C | |
| Fumaric Acid SCHEMBL4298946 | 0.92 | KCNH2 (0.61) | KCNH2KCNQ1CACNA1C | |
| Fumaric Acid SCHEMBL4301447 | 0.92 | KCNH2 (0.61) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL12046845 | 0.92 | KCNH2 (0.60) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL4301421 | 0.91 | KCNH2 (0.58) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL4302532 | 0.91 | KCNH2 (0.58) | KCNH2KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL4299502 | 0.90 | KCNH2 (0.57) | KCNH2KCNQ1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992628-A1 | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones | GLAXO GROUP LIMITED (GB) | 2008-11-19 | — | — | EP | disclosed |
| WO-2008009700-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | GLAXO GROUP LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |