Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263409 | 0.93 | KMT2A (0.57) | KMT2AMEN1MAPTTP53POLB | |
| SCHEMBL264263 | 0.88 | MEN1 (0.58) | KMT2AMEN1MAPTTP53POLB | |
| SCHEMBL264808 | 0.83 | MEN1 (0.62) | KMT2AMEN1MAPTTP53POLB | |
| SCHEMBL264897 | 0.83 | MEN1 (0.62) | KMT2AMEN1MAPTTP53POLB | |
| SCHEMBL264528 | 0.82 | KMT2A (0.64) | KMT2AMEN1MAPTTP53POLB | |
| SCHEMBL264007 | 0.82 | CYP3A4 (0.57) | KMT2AMEN1MAPTTP53POLB | |
| SCHEMBL14023510 | 0.80 | KMT2A (0.67) | KMT2AMEN1MAPTTP53POLB | |
| SCHEMBL264431 | 0.78 | MAPT (0.53) | KMT2AMEN1MAPTPOLBRXFP1 | |
| SCHEMBL14023515 | 0.78 | MEN1 (0.51) | KMT2AMEN1MAPTTP53POLB | |
| SCHEMBL268845 | 0.77 | CYP3A4 (0.59) | KMT2AMEN1MAPTTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008138126-A1 | BICYCLIC PYRIMIDINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2008-11-20 | — | — | WO | disclosed |