SCHEMBL14024022

SCHEMBL14024022

CC(C)(C)[Si](C)(C)OCc1cnn(-c2ccc(N3C[C@H](CI)OC3=O)cc2F)c1

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 12/20 0.42
MAOA P21397 7/20 0.42
CALML3 P27482 5/20 0.42
LMNA P02545 1/20 0.42
PTGS1 P23219 1/20 0.42
SDHA P31040 1/20 0.42
KCNH2 Q12809 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3764033 0.92 CALML3 (0.48) MAOBMAOACALML3LMNAPTGS1
SCHEMBL3747789 0.88 MAOB (0.42) MAOBMAOACALML3LMNAPTGS1
SCHEMBL14025109 0.87 MAOB (0.37) MAOBMAOACALML3LMNAPTGS1
SCHEMBL3751977 0.81 CALML3 (0.44) MAOBMAOACALML3
SCHEMBL14024128 0.79 MAOB (0.47) MAOBMAOACALML3LMNAPTGS1
SCHEMBL13081519 0.77 CALML3 (0.58) MAOBMAOACALML3LMNAPTGS1
SCHEMBL3757473 0.75 CALML3 (0.48) MAOBMAOACALML3LMNAPTGS1
SCHEMBL5833572 0.75 CALML3 (0.48) MAOBMAOACALML3LMNAPTGS1
SCHEMBL7837834 0.74 CALML3 (0.46) MAOBMAOACALML3LMNAPTGS1
SCHEMBL7837836 0.74 CALML3 (0.46) MAOBMAOACALML3LMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008143649-A2 NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS DR. REDDY'S LABORATORIES LIMITED (IN) 2008-11-27 WO disclosed