Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 16/20 | 0.56 |
| ▸ | CHUK | O15111 | 1/20 | 0.56 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4942324 | 0.99 | IKBKB (0.55) | IKBKBCHUKCDK1CDK2CHEK2 | |
| SCHEMBL14028498 | 0.84 | IKBKB (0.56) | IKBKBCHUKCDK1CDK2CHEK2 | |
| Hydrochloric Acid SCHEMBL4944296 | 0.83 | IKBKB (0.55) | IKBKBCHUKCDK1CDK2CHEK2 | |
| SCHEMBL7197710 | 0.82 | IKBKB (0.52) | IKBKBCHUKCDK1CDK2CHEK2 | |
| Hydrochloric Acid SCHEMBL4945004 | 0.81 | IKBKB (0.51) | IKBKBCHUKCDK1CDK2CHEK2 | |
| SCHEMBL14028464 | 0.81 | IKBKB (0.64) | IKBKBCHUKCDK1CDK2 | |
| Hydrochloric Acid SCHEMBL4947782 | 0.80 | IKBKB (0.63) | IKBKBCHUKCDK1CDK2 | |
| SCHEMBL14028470 | 0.79 | IKBKB (0.70) | IKBKBCHUKCDK1CDK2CHEK2 | |
| Hydrochloric Acid SCHEMBL4945343 | 0.78 | IKBKB (0.69) | IKBKBCHUKCDK1CDK2CHEK2 | |
| SCHEMBL4942340 | 0.77 | SMARCA2 (0.43) | IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435743-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2008-10-14 | — | — | US | disclosed |
| US-7435743-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2008-10-14 | — | — | US | disclosed |
| US-7232909-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2007-06-19 | — | — | US | disclosed |
| US-7232909-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2007-06-19 | — | — | US | disclosed |