Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 20/20 | 0.65 |
| ▸ | CHUK | O15111 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4946011 | 0.99 | IKBKB (0.64) | IKBKBCHUK | |
| SCHEMBL4600986 | 0.85 | IKBKB (0.75) | IKBKBCHUK | |
| SCHEMBL14028526 | 0.84 | IKBKB (0.70) | IKBKBCHUK | |
| Hydrochloric Acid SCHEMBL4947773 | 0.84 | IKBKB (0.69) | IKBKBCHUK | |
| SCHEMBL14492126 | 0.81 | IKBKB (0.67) | IKBKBCHUK | |
| SCHEMBL14028525 | 0.79 | IKBKB (0.65) | IKBKBCHUK | |
| SCHEMBL1726425 | 0.79 | IKBKB (1.00) | IKBKBCHUK | |
| SCHEMBL30337765 | 0.79 | IKBKB (1.00) | IKBKBCHUK | |
| Hydrochloric Acid SCHEMBL4945749 | 0.79 | IKBKB (0.64) | IKBKBCHUK | |
| Hydrochloric Acid SCHEMBL30341860 | 0.78 | IKBKB (0.98) | IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435743-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2008-10-14 | — | — | US | disclosed |
| US-7435743-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2008-10-14 | — | — | US | disclosed |
| US-7232909-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2007-06-19 | — | — | US | disclosed |
| US-7232909-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2007-06-19 | — | — | US | disclosed |