Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 5/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4939836 | 0.89 | PRMT5 (0.47) | PRMT5ALOX5APFEN1CCNT1CCNA2 | |
| SCHEMBL7019154 | 0.88 | PRMT5 (0.46) | PRMT5ALOX5APFEN1CCNT1CCNA2 | |
| SCHEMBL14046479 | 0.87 | PRMT5 (0.48) | PRMT5ALOX5APFEN1CCNT1CCNA2 | |
| SCHEMBL4944836 | 0.85 | PRMT5 (0.47) | PRMT5ALOX5APFEN1CCNT1CCNA2 | |
| SCHEMBL4943046 | 0.85 | PRMT5 (0.47) | PRMT5ALOX5APFEN1CCNT1CCNA2 | |
| SCHEMBL4946466 | 0.85 | PRMT5 (0.47) | PRMT5ALOX5APFEN1CCNT1CCNA2 | |
| SCHEMBL4940870 | 0.85 | PRMT5 (0.47) | PRMT5ALOX5APFEN1CCNT1CCNA2 | |
| SCHEMBL4942308 | 0.84 | PRMT5 (0.46) | PRMT5ALOX5APFEN1CCNT1CCNA2 | |
| SCHEMBL4939088 | 0.83 | IKBKB (0.53) | PRMT5ALOX5APFEN1CCNT1CCNA2 | |
| SCHEMBL4945989 | 0.83 | PRMT5 (0.46) | PRMT5ALOX5APFEN1CCNT1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435743-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2008-10-14 | — | — | US | disclosed |
| US-7435743-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2008-10-14 | — | — | US | disclosed |
| US-7232909-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2007-06-19 | — | — | US | disclosed |
| US-7232909-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2007-06-19 | — | — | US | disclosed |