Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 2/20 | 0.44 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.44 |
| ▸ | HPGDS | O60760 | 2/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.38 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028529 | 0.91 | SMARCA2 (0.46) | SMARCA2SMARCA4PBRM1HPGDSIKBKB | |
| SCHEMBL4939767 | 0.85 | SMARCA2 (0.44) | SMARCA2SMARCA4PBRM1HPGDSIKBKB | |
| SCHEMBL4942466 | 0.84 | IKBKB (0.45) | SMARCA2SMARCA4PBRM1HPGDSIKBKB | |
| SCHEMBL4939775 | 0.84 | SMARCA2 (0.44) | SMARCA2SMARCA4PBRM1HPGDSIKBKB | |
| SCHEMBL7025589 | 0.82 | SMARCA2 (0.44) | SMARCA2SMARCA4PBRM1HPGDSIKBKB | |
| SCHEMBL4944898 | 0.80 | HPGD (0.47) | SMARCA2SMARCA4PBRM1HPGDSIKBKB | |
| SCHEMBL14046508 | 0.79 | SMARCA2 (0.54) | SMARCA2SMARCA4PBRM1HPGDSIKBKB | |
| SCHEMBL14028510 | 0.78 | SMARCA2 (0.53) | SMARCA2SMARCA4PBRM1HPGDSIKBKB | |
| SCHEMBL4942443 | 0.78 | IKBKB (0.41) | SMARCA2SMARCA4PBRM1IKBKB | |
| SCHEMBL14028531 | 0.77 | IKBKB (0.55) | IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435743-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2008-10-14 | — | — | US | disclosed |
| US-7435743-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2008-10-14 | — | — | US | disclosed |
| US-7232909-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2007-06-19 | — | — | US | disclosed |
| US-7232909-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2007-06-19 | — | — | US | disclosed |