Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 18/20 | 0.59 |
| ▸ | CHUK | O15111 | 1/20 | 0.59 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4946313 | 0.99 | IKBKB (0.58) | IKBKBCHUKIRAK4 | |
| SCHEMBL4946401 | 0.91 | IKBKB (0.61) | IKBKBCHUK | |
| SCHEMBL14028581 | 0.83 | IKBKB (0.60) | IKBKBCHUK | |
| Hydrochloric Acid SCHEMBL4945782 | 0.83 | IKBKB (0.59) | IKBKBCHUK | |
| SCHEMBL14028336 | 0.82 | IKBKB (0.58) | IKBKBCHUK | |
| SCHEMBL14028342 | 0.81 | IKBKB (0.56) | IKBKBCHUK | |
| SCHEMBL14492188 | 0.81 | IKBKB (0.57) | IKBKBCHUK | |
| SCHEMBL4945974 | 0.81 | IKBKB (0.57) | IKBKBCHUK | |
| SCHEMBL14028337 | 0.81 | IKBKB (0.57) | IKBKBCHUK | |
| SCHEMBL14492189 | 0.81 | IKBKB (0.56) | IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435743-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2008-10-14 | — | — | US | disclosed |
| US-7435743-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2008-10-14 | — | — | US | disclosed |
| US-7232909-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2007-06-19 | — | — | US | disclosed |
| US-7232909-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2007-06-19 | — | — | US | disclosed |