Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 5/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | BCL9 | O00512 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4947771 | 0.93 | PRMT5 (0.43) | PRMT5TLR9ALOX5APFEN1BCL9 | |
| SCHEMBL14339664 | 0.92 | PRMT5 (0.42) | PRMT5TLR9ALOX5APFEN1BCL9 | |
| SCHEMBL4947749 | 0.91 | HPGD (0.41) | PRMT5TLR9ALOX5APFEN1BCL9 | |
| SCHEMBL4946420 | 0.90 | PRMT5 (0.42) | PRMT5TLR9ALOX5APFEN1BCL9 | |
| SCHEMBL4940406 | 0.90 | PRMT5 (0.42) | PRMT5TLR9ALOX5APFEN1BCL9 | |
| SCHEMBL4946491 | 0.90 | SCN9A (0.47) | PRMT5TLR9ALOX5APFEN1BCL9 | |
| SCHEMBL4947725 | 0.90 | PRMT5 (0.39) | PRMT5TLR9ALOX5APFEN1BCL9 | |
| SCHEMBL4947196 | 0.88 | PRMT5 (0.43) | PRMT5TLR9ALOX5APFEN1BCL9 | |
| SCHEMBL4945773 | 0.88 | PRMT5 (0.41) | PRMT5TLR9ALOX5APFEN1BCL9 | |
| SCHEMBL14028576 | 0.87 | PRMT5 (0.42) | PRMT5TLR9ALOX5APFEN1BCL9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435743-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2008-10-14 | — | — | US | disclosed |
| US-7435743-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2008-10-14 | — | — | US | disclosed |