Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15359366 | 0.83 | GRIA1 (0.46) | — | |
| SCHEMBL4324321 | 0.82 | CYP3A4 (0.55) | CYP3A4TSHRPRSS1TMPRSS15GAA | |
| SCHEMBL17017540 | 0.80 | CYP3A4 (0.51) | CYP3A4TSHRGAAMAPTCRHBP | |
| SCHEMBL19728217 | 0.78 | GRIA1 (0.56) | PRSS1 | |
| SCHEMBL16589731 | 0.78 | GRIA1 (0.64) | — | |
| SCHEMBL16589702 | 0.78 | GRIA1 (0.40) | OPRM1OPRD1OPRK1 | |
| SCHEMBL12192356 | 0.77 | SLC7A5 (0.47) | — | |
| SCHEMBL22403191 | 0.76 | GAA (0.53) | CYP3A4TSHRGAAMAPTCRHBP | |
| SCHEMBL15314125 | 0.76 | GAA (0.53) | CYP3A4TSHRGAAMAPTCRHBP | |
| SCHEMBL3820586 | 0.75 | CHRM1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439258-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM (CANADA) LTD (CA) | 2008-10-21 | — | — | US | disclosed |
| US-7439258-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM (CANADA) LTD (CA) | 2008-10-21 | — | — | US | disclosed |