Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.32 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7246754 | 1.00 | AR (0.53) | ARMAPTALDH1A1PKMHPGD | |
| SCHEMBL4042115 | 0.88 | AR (0.67) | ARMAPTALDH1A1PKMHPGD | |
| SCHEMBL4040077 | 0.88 | AR (0.67) | ARMAPTALDH1A1PKMHPGD | |
| SCHEMBL4040068 | 0.88 | AR (0.67) | ARMAPTALDH1A1PKMHPGD | |
| SCHEMBL4037215 | 0.80 | AR (0.57) | ARMAPTALDH1A1PKMHPGD | |
| SCHEMBL5865743 | 0.76 | MAPT (0.46) | MAPTALDH1A1PKMHPGDHSD17B10 | |
| SCHEMBL5865742 | 0.76 | MAPT (0.46) | MAPTALDH1A1PKMHPGDHSD17B10 | |
| SCHEMBL6212655 | 0.76 | MAPT (0.46) | MAPTALDH1A1PKMHPGDHSD17B10 | |
| SCHEMBL5865739 | 0.76 | MAPT (0.46) | MAPTALDH1A1PKMHPGDHSD17B10 | |
| SCHEMBL3189275 | 0.72 | GAA (0.58) | MAPTALDH1A1PKMHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432267-B2 | Fused cyclic modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMAPNY (US) | 2008-10-07 | — | — | US | disclosed |