Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.70 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | TGM1 | P22735 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044371 | 0.89 | AR (0.67) | ARCTSBGAA | |
| SCHEMBL4039836 | 0.88 | AR (0.65) | ARCTSBGAA | |
| SCHEMBL6375514 | 0.88 | AR (0.65) | ARCTSBGAA | |
| SCHEMBL5092450 | 0.88 | AR (0.65) | ARCTSBGAA | |
| SCHEMBL5099264 | 0.88 | AR (0.65) | ARCTSBGAA | |
| SCHEMBL4037420 | 0.88 | AR (0.65) | ARCTSBGAA | |
| SCHEMBL5099093 | 0.87 | AR (0.78) | ARCTSBGAA | |
| SCHEMBL5092473 | 0.86 | AR (0.64) | ARCTSBGAA | |
| SCHEMBL7209729 | 0.86 | AR (0.64) | ARCTSBGAA | |
| SCHEMBL5093823 | 0.86 | AR (0.68) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432267-B2 | Fused cyclic modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMAPNY (US) | 2008-10-07 | — | — | US | disclosed |