Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.31 |
| ▸ | CHRNB3 | Q05901 | 4/20 | 0.31 |
| ▸ | CHRNA6 | Q15825 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16339311 | 0.83 | CA1 (0.34) | ALDH1A1NPC1ACHEKMT2AMEN1 | |
| SCHEMBL3652927 | 0.83 | CA1 (0.34) | ALDH1A1NPC1ACHEKMT2AMEN1 | |
| SCHEMBL29083621 | 0.83 | CA1 (0.34) | ALDH1A1NPC1ACHEKMT2AMEN1 | |
| SCHEMBL19025162 | 0.83 | CA1 (0.34) | ALDH1A1NPC1ACHEKMT2AMEN1 | |
| SCHEMBL18497723 | 0.83 | CA1 (0.34) | ALDH1A1NPC1ACHEKMT2AMEN1 | |
| SCHEMBL25349073 | 0.83 | CA1 (0.34) | ALDH1A1NPC1ACHEKMT2AMEN1 | |
| SCHEMBL19025163 | 0.83 | CA1 (0.34) | ALDH1A1NPC1ACHEKMT2AMEN1 | |
| SCHEMBL16339312 | 0.83 | CA1 (0.34) | ALDH1A1NPC1ACHEKMT2AMEN1 | |
| SCHEMBL21195937 | 0.83 | CA1 (0.34) | ALDH1A1NPC1ACHEKMT2AMEN1 | |
| SCHEMBL19023326 | 0.83 | CA1 (0.34) | ALDH1A1NPC1ACHEKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293758-A1 | Combination of a Steroid Sulfatase Inhibitor and an Ascomycin | NOVARTIS AG (CH) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293758-A1 | Combination of a Steroid Sulfatase Inhibitor and an Ascomycin | STS, ARSA, CYP17A1 | ALDH1A1 676/4885NPC1 1816/4885ACHE 3650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.