Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CASP1 | P29466 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.58 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14035054 | 0.79 | HPGD (0.40) | MEN1KMT2AHPGDSMN1; SMN2IDO1 | |
| SCHEMBL4774676 | 0.77 | KMT2A (0.45) | HIF1AMEN1CYP3A4KMT2AHPGD | |
| Dichlorophen SCHEMBL29349447 | 0.75 | CYP3A4 (1.00) | HIF1AMEN1CYP3A4KMT2AHPGD | |
| Dichlorophen SCHEMBL29524636 | 0.75 | CYP3A4 (1.00) | HIF1AMEN1CYP3A4KMT2AHPGD | |
| Dichlorophen SCHEMBL18052 | 0.75 | CYP3A4 (1.00) | HIF1AMEN1CYP3A4KMT2AHPGD | |
| Dichlorophen SCHEMBL9109126 | 0.75 | CYP3A4 (1.00) | HIF1AMEN1CYP3A4KMT2AHPGD | |
| SCHEMBL14034918 | 0.74 | PTGER1 (0.58) | MAPTADORA3ALDH1A1 | |
| Dichlorophen SCHEMBL735904 | 0.73 | CYP3A4 (0.95) | HIF1AMEN1CYP3A4KMT2AHPGD | |
| Dichlorophen SCHEMBL2471883 | 0.73 | CYP3A4 (0.95) | HIF1AMEN1CYP3A4KMT2AHPGD | |
| SCHEMBL19236232 | 0.73 | MEN1 (0.77) | HIF1AMEN1CYP3A4KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | PTGER1, PTGER2, PTGER3 | HIF1A 1919/4885MEN1 912/4885CYP3A4 565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.